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Wiley_ADVANCED FUNCTIONAL MATERIALS

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Volume35, Issue50

December 9, 2025

e72865


Surface Fluidic Microneedle Patches for Lymphatic Delivery of Diagnostic and Therapeutic Agents (Adv. Funct. Mater. 50/2025)

In their Research Article (10.1002/adfm.202513324), Jae Yong Jeon, Hyunsik Yoon, and co-workers present a surface fluidic microneedle patch (SFMNP). The micro- and nano-grooves on the SFMNP synergistically maximize capillary force, allowing ICG (green square molecules) to be injected into lymphatic vessels effectively. It enables precise infusion into the interstitium, real-time tracking, and minimally invasive delivery, optimized for lymphatic-targeted therapy and diagnostics.


  • Hwayeong Cheon
  • Hyewon Choi
  • Sohyun Kim
  • Ji Hoon Kim
  • Bumchul Kim
  • Jihee Kim
  • Sieun Kim
  • Jae Yong Jeon
  • Hyunsik Yoon


https://advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.72865


Image created by minjeong Kim / Nanosphere